-
ARTIGO ORIGINAL
Selenium concentrations in elderly people with Alzheimer’s disease: a cross-sectional study with control group
- Carlos Queiroz do Nascimento
, - João Araújo Barros-Neto ,
- Nathalia Fidelis Lins Vieira ,
- José Antonio Menezes-Filho ,
- Sabrina Joanny Felizardo Neves , [ ... ],
- Sonia Oliveira Lima
07-05-2021
Resumo
ARTIGO ORIGINALSelenium concentrations in elderly people with Alzheimer’s disease: a cross-sectional study with control group
Revista Brasileira de Enfermagem. 2021;74(suppl 2):e20200984
07-05-2021DOI 10.1590/0034-7167-2020-0984
- Carlos Queiroz do Nascimento ,
- João Araújo Barros-Neto ,
- Nathalia Fidelis Lins Vieira ,
- José Antonio Menezes-Filho ,
- Sabrina Joanny Felizardo Neves ,
- Sonia Oliveira Lima
Visualizações0Ver maisABSTRACT
Objective:
To investigate possible differences in plasma and erythrocyte concentrations of selenium among elderly with and without a diagnosis of Alzheimer’s disease (AD).
Methods:
Cross-sectional study, performed with an elderly group with Alzheimer’s disease, diagnosed by a geriatric doctor, and compared to an elderly group without the disease, equaling gender, education, and age. Atomic absorption spectrophotometry determined plasma and erythrocyte concentrations of total selenium (Set).
Results:
The mean age was 74.41±7.1 years in the Alzheimer’s disease group and 71.46±5.1 years among the control group. The Alzheimer’s disease group presented lower plasma concentrations (mean of 45.29±14.51 µg/dL vs. 55.14±14.01 µg/dL; p=0.004), and erythrocyte Set (median of 56.36 µg/L vs. 76.96 µg/L; p<0.001). The logistic regression model indicated an association between erythrocyte Set concentrations and diagnosis of Alzheimer’s disease (p=0.028).
Conclusion:
Elderly with Alzheimer’s disease present lower selenium concentrations in the evaluated organic compartments.
Visualizações0
Resumo
ARTIGO ORIGINALSelenium concentrations in elderly people with Alzheimer’s disease: a cross-sectional study with control group
Revista Brasileira de Enfermagem. 2021;74(suppl 2):e20200984
07-05-2021DOI 10.1590/0034-7167-2020-0984
- Carlos Queiroz do Nascimento ,
- João Araújo Barros-Neto ,
- Nathalia Fidelis Lins Vieira ,
- José Antonio Menezes-Filho ,
- Sabrina Joanny Felizardo Neves ,
- Sonia Oliveira Lima
Visualizações0Ver maisABSTRACT
Objective:
To investigate possible differences in plasma and erythrocyte concentrations of selenium among elderly with and without a diagnosis of Alzheimer’s disease (AD).
Methods:
Cross-sectional study, performed with an elderly group with Alzheimer’s disease, diagnosed by a geriatric doctor, and compared to an elderly group without the disease, equaling gender, education, and age. Atomic absorption spectrophotometry determined plasma and erythrocyte concentrations of total selenium (Set).
Results:
The mean age was 74.41±7.1 years in the Alzheimer’s disease group and 71.46±5.1 years among the control group. The Alzheimer’s disease group presented lower plasma concentrations (mean of 45.29±14.51 µg/dL vs. 55.14±14.01 µg/dL; p=0.004), and erythrocyte Set (median of 56.36 µg/L vs. 76.96 µg/L; p<0.001). The logistic regression model indicated an association between erythrocyte Set concentrations and diagnosis of Alzheimer’s disease (p=0.028).
Conclusion:
Elderly with Alzheimer’s disease present lower selenium concentrations in the evaluated organic compartments.
- Carlos Queiroz do Nascimento
-
REVIEW
Biological activities: anti-infectious, antioxidant and healing of the vegetable species Jatropha multifida
- Daniglayse Santos Vieira ,
- Fabianny Torres de Oliveira ,
- Jorge Andrés Garcia Suarez ,
- Davi Porfírio da Silva ,
- Thais Honório Lins Bernardo , [ ... ],
- Maria Lysete de Assis Bastos
05-28-2021
Resumo
REVIEWBiological activities: anti-infectious, antioxidant and healing of the vegetable species Jatropha multifida
Revista Brasileira de Enfermagem. 2021;74(2):e20200451
05-28-2021DOI 10.1590/0034-7167-2020-0451
- Daniglayse Santos Vieira ,
- Fabianny Torres de Oliveira ,
- Jorge Andrés Garcia Suarez ,
- Davi Porfírio da Silva ,
- Thais Honório Lins Bernardo ,
- Maria Lysete de Assis Bastos
Visualizações0Ver maisABSTRACT
Objective:
to investigate the biological activities of interest to the health of Jatropha multifida plant species in published scientific literature.
Methods:
this is an integrative review, with searches between May and June 2019, using the descriptors, combined through the Boolean operator AND, Jatropha multifida, anti-infective agents, wound healing, cytotoxicity and antioxidants, in LILACS, BDENF, MEDLINE, SciFinder, Web of Science and Scopus databases and in the virtual libraries SciELO and ScienceDirect.
Results:
twelve publications were retrieved that showed nine biological activities. The antioxidant activity was reported in 04 (33.33%) studies; antimicrobial and anticancer, addressed by 03 (25%) and 02 (16.66%); anti-inflammatory, anti-melanin deposition, healing, antiophidic, purgative and anti-influenza, seen in 01 (8.33%) each.
Final considerations:
although scarce, the published scientific production highlights the biological potential of J. multifida and supports the need for further studies.
Visualizações0Resumo
REVIEWBiological activities: anti-infectious, antioxidant and healing of the vegetable species Jatropha multifida
Revista Brasileira de Enfermagem. 2021;74(2):e20200451
05-28-2021DOI 10.1590/0034-7167-2020-0451
- Daniglayse Santos Vieira ,
- Fabianny Torres de Oliveira ,
- Jorge Andrés Garcia Suarez ,
- Davi Porfírio da Silva ,
- Thais Honório Lins Bernardo ,
- Maria Lysete de Assis Bastos
Visualizações0Ver maisABSTRACT
Objective:
to investigate the biological activities of interest to the health of Jatropha multifida plant species in published scientific literature.
Methods:
this is an integrative review, with searches between May and June 2019, using the descriptors, combined through the Boolean operator AND, Jatropha multifida, anti-infective agents, wound healing, cytotoxicity and antioxidants, in LILACS, BDENF, MEDLINE, SciFinder, Web of Science and Scopus databases and in the virtual libraries SciELO and ScienceDirect.
Results:
twelve publications were retrieved that showed nine biological activities. The antioxidant activity was reported in 04 (33.33%) studies; antimicrobial and anticancer, addressed by 03 (25%) and 02 (16.66%); anti-inflammatory, anti-melanin deposition, healing, antiophidic, purgative and anti-influenza, seen in 01 (8.33%) each.
Final considerations:
although scarce, the published scientific production highlights the biological potential of J. multifida and supports the need for further studies.
- Daniglayse Santos Vieira
Antioxidants Archives - Revista Brasileira de Enfermagem
